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Discover 2025-26 Itinerary

How to reserve your seat aboard Serenade of the Seas

Departing from Colón every Saturday from October 2025 to April 2026, Serenade of the Seas offers various routes to the Caribbean islands and Cartagena, Colombia.

Serenade of the Seas Panama

When we imagine booking a luxurious cruise aboard the Serenade of the Seas…

We might see it like a complicated or costly process, but in reality, it’s surprisingly easy and accessible.

With just a minimum reservation of $250, we can secure our spot on one of the many Caribbean and Colombian adventures offered by the Serenade of the Seas, allowing us to plan ahead without the stress of paying everything upfront. This flexible approach helps us manage our vacation budget wisely, making it possible to lock in our dream getaway today while spreading the payments comfortably over time.

All payment agreements are customized for comfort and all reserved cruise packages must be fully paid 90 days before departure.

Contact us for more information!

Contact us for more information

Serenade of the Seas 2025-26 Itinerary

Please pay attention to route description as they may change according to weather, availability, logistics, etc.  

All routes depart from Colón in Panamá and make a stop in Cartagena, Colombia.  Other destinations included are at least 2 of the following options: Oranjestad (Aruba), Willemstad (Curacao) and/or Kralendijk (Bonaire)  See more about destinations visited by the Serenade of the Seas 2025-2026

Choose your preferred route and contact us to secure your reservation for your next Caribbean vacation.

About prices and cabins

All prices listed are per person for a double cabin and include taxes, room rates, and a deluxe beverage package.  Prices in USD.

See more about…

October 2025

October 18th – 25th, 2025

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Window
1,344.00
Balcony
1,614.00

October 25th – November 1st, 2025

Route: Colón, Panamá | Cartagena, Colombia | Willemstad, Curacao | Oranjestad, Aruba | Colón, Panamá

Double Cabin price per person

Interior
1,274.00
Window
1,394.00
Balcony
1,664.00
October 2025

November 2025

November 8th – 15th, 2025

Route: Colón, Panamá | Cartagena, Colombia | Kralendijk, Bonaire | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,289.00
Window
1,403.00
Balcony
1,679.00

November 15th – 22nd, 2025

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,374.00
Window
1,489.00
Balcony
1,759.00

November 22nd – 29th, 2025

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,354.00
Window
1,604.00
Balcony
1,839.00

November 29th – December 6th, 2025

Route: Colón, Panamá | Cartagena, Colombia | Kralendijk, Bonaire | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,474.00
Window
1,599.00
Balcony
1,859.00
November 2025

December 2025

December 6th – 12th, 2025

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,399.00
Window
1,529.00
Balcony
1,789.00

December 12th – 20th, 2025

Route: Colón, Panamá | Cartagena, Colombia | Kralendijk, Bonaire | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,399.00
Window
1,529.00
Balcony
1,789.00

December 20th – 27th, 2025

Route: Colón, Panamá | Cartagena, Colombia | Willemstad, Curacao | Oranjestad, Aruba | Colón, Panamá

Double Cabin price per person

Interior
1,814.00
Window
1,929.00
Balcony
2,203.00
December 2025

January 2026

January 3rd – 10th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Kralendijk, Bonaire | Oranjestad, Aruba | Colón, Panamá

Double Cabin price per person

Interior
1,474.00
Window
1,599.00
Balcony
1,864.00

January 10th – 17th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,486.00
Window
1,605.00
Balcony
1,879.00

January 24th – 31st, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Kralendijk, Bonaire | Colón, Panamá

Double Cabin price per person

Interior
1,329.00
Window
1,434.00
Balcony
1,719.00

January 31st – February 7th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Kralendijk, Bonaire | Colón, Panamá

Double Cabin price per person

Balcony
1,679.00
January 2026

February 2026

February 7th – 14th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Kralendijk, Bonaire | Colón, Panamá

Double Cabin price per person

Window
1,419.00
Balcony
1,689.00

February 21st – 28th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Kralendijk, Bonaire | Oranjestad, Aruba | Colón, Panamá

Double Cabin price per person

Interior
1,349.00
Window
1,480.00

February 28th – March 7th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Kralendijk, Bonaire | Oranjestad, Aruba | Colón, Panamá

Double Cabin price per person

Interior
1,474.00
Window
1,599.00
Balcony
1,864.00
February 2026

March 2026

March 7th – 14th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,479.00
Balcony
1,869.00

March 14h – 21st, 2026

Route: Colón, Panamá | Cartagena, Colombia | Willemstad, Curacao | Oranjestad, Aruba | Colón, Panamá

Double Cabin price per person

Interior
1,479.00
Balcony
1,869.00

March 21st – 28th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,479.00
Window
1,604.00
Balcony
1,869.00

March 28th – April 4th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Kralendijk, Bonaire | Colón, Panamá

Double Cabin price per person

Interior
1,814.00
Window
1,929.00
Balcony
2,203.00
March 2026

April 2026

April 4th – 11th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Oranjestad, Aruba | Willemstad, Curacao | Colón, Panamá

Double Cabin price per person

Interior
1,674.00
Window
1,894.00
Balcony
2,024.00

April 11th – 18th, 2026

Route: Colón, Panamá | Cartagena, Colombia | Willemstad, Curacao | Oranjestad, Aruba | Colón, Panamá

Double Cabin price per person

Interior
1,599.00
Balcony
1,979.00
April 2026